Bioperine is an extract from the fruit of Piper nigrum L (black pepper) or Piper longum L (long pepper) that contains 95 percent of piperine. Black pepper is a common household spice. Extract from black pepper has also been used extensively as a medicine. To reach the greatest quality during the harvest, the pepper is reaped before ripening and after that is placed to dry under the sun rays. Bioperine is known for its effect to enhance the efficiency of many supplement nutrients. Bioperine acts to enhance the body’s natural therogenic activity – giving the name thermonutrient. This enhancement brings about increased metabolic rate creating demand for supple of many nutrients such as vitamins, minerals, herbals, amino acids. It sets in motion a process that brings about better digestion and faster gastrointestinal absorption.

Caffeine- The bitter, white crystalline xanthine alkaloid caffeine is found in tea, coffee, soft drinks, chocolates, pain relievers, and a variety of over the counter medications. It is a psychoactive stimulant drug that causes increased alertness by stimulating the central nervous system. For the same reason, many people feel more energetic after consuming it. It even elevates the mood but these effects do not last for long. The effects of caffeine usually last for about five to six hours, though caffeine sensitivity varies from person to person. It has been found that people who consume lot of caffeine on a daily basis soon develop less sensitivity and may need to increase their intake to enjoy the same effect. Being a diuretic, a person consuming caffeine may have to urinate more often.

Green Tea Extract is utilized to increase fat metabolism as well as aide in weight loss and weight loss management.

Sclareolide, a fermented clary sage compound, is a plant terpenoid. Terpenoids are a diverse category of organic chemicals occurring in natural form. Sclareolide is a natural muscle relaxer and used to relieve backaches, muscle cramps as well as muscle spasms. Besides this, sclareolide also helps in maintaining and building lean body mass. Since it is known to have excellent thermogenic properties, it is widely used in weight loss supplements under the name of Norambrolide. It works by directly increasing cAMP levels and boosting the activity rate of lipolysis through the energy metabolism, Cyclic AMP. The best way for dieters to shed more body fat is to take a sclareolide dose in combination with a thermogenic supplement. This way, dieters can be assured of burning more calories easily.

Synephrine is a drug that is deemed to selectively bind to and also activate alpha adrenergic receptors. Mainly used as a vasoconstrictor in asthma, glaucoma, circulatory failure and nasal congestion, this compound is currently propagated as a weight loss agent. The alleged function synephrine is providing include fat burning, energy level and metabolism increase and promotion of weight loss. Synephrine, also known as oxedrine, is the widely accepted replacement for ephedrine. The natural source of synephrine is the citrus aurantium fruit, better known as bitter orange. Bitter orange extracts, which contain synephrine, are known to stimulate the alpha-1 adrenergic receptor, thereby constricting blood vessels and increasing the heart rate as well as blood pressure, effecting in an increased energy use.

Synthetic Guggulsteroneswere first intended for use as a drug and is now used as a weight loss product and weight management product with the possibility of some side effects. More studies need to be done on this.

Vinpocetine, a derivative alkaloid of vincamine, is actually semi synthetic in nature. It is an extract from the It is an extract from the periwinkle vinca minor. Vinpocentine is used because it has neuroprotective effects and also helps in enhancing the cerebral blood flow. In Eastern Europe, it is also used as a drug to treat cerebrovascular disorders along with age related memory impairment. It is also extensively marketed as a supplement for vasodilation. It is also used to improve the memory since it plays the role of a nootropic. Vinpocentine is therefore used in supporting brain function. It helps in enhancing concentration and memory by activating cerebral metabolism. In the body building world, vinpocetine is often used a vasodilator. However, no research has been done so far on the effect of vinpocentine in the body building.

Yohimbe contains an alkaline called yohimbine. It releases a hormone that stimulates sexual organs and blood flow in the genitals known as norepinephrine. Yohimbe is known treatment for sexual dysfunctions such as male impotence. It also has aphrodisiac property that improves the libido for both men and women. Yohimbe also helps in weight loss by increasing lypolysis by enhancing the excretion of norephinephrine. It also has antioxidant properties. It may also improve and alleviate exhaustion and feebleness. Yohimbe also helps alleviate the mood by blocking the enzyme called monoamine oxidase that may cause depression. Yohimbe also causes vasodilation that helps lower blood pressure.