Betaine HCL, or betaine hydrochloride, is not an essential nutrient, but it helps in absorption of proteins, vitamin B12, iron and calcium and helps in the digestive tract with the protein and fat breaking up abilities. It is a supplemental source of hydrochloric acid, with a low pH level. Besides the obvious use against indigestion and heartburn, other uses have been proclaimed for betaine HCL, such as lowering the homocysteine level, helping with thyroid conditions and others. With progressing age, hydrochloric acid and digestive enzymes may decrease, with a poor digestion as a result. With betaine HCL, when taken at the beginning of a meal, proper digestion can be accomplished. Betaine HCL is most commonly provided with the addition of pepsin, a digestive enzyme.

Choline Bitartrate , or choline for short, is an essential nutrient involved in many bodily actions such as the structure and function of cells and metabolic functions.

Chromium Polynicotinate is a product associated with medical food. It is used as a nutritional support in diabetes related conditions. Chromium polynicotinate is said to be nothing but an assimilated form of chromium. It is said to be the most effective type of chromium. It is absorbed by the body in its biologically active form. It is also crucial to the process of synthesis of fats, protein and cholesterol. Chromium polynicotinate if taken in monitored dosage can help stabilize blood sugar levels. This proves beneficial for people suffering from diabetes as well as hypoglycemia. Its main property is to produce insulin. Therefore, it helps in the metabolism of glucose. This type of chromium polynicotinate helps in the production of anabolic effects which have no side effects. On the other hand, they help in keeping the fat cells away from the muscle cells.

Guarana is a climbing plant of the Sapindaceae family native to the Amazon basin. Guarana is best known for its fruit and seeds. Guarana extracts contain naturally high amounts of caffeine which the plant uses in defense against pathogens. Its extracts are a natural and abundant source of caffeine in most parts of the world. It is added to soft drinks, herbal tea, energy shots and used in capsules. The extracts have a positive effect on cognition and they also increase memory retention and physical endurance. A 2007 study on human pilots showed its positive effects on memory, alertness and mood. It is also reported to have antioxidant and antibacterial effects.

Gymnema Sylvestre, also known as Gurmar and Meshashringi, or 'sugar destroyer'. Gymnema Sylvestre leaves have a blood sugar lowering effect. The leaf extracts also contain gymnemic acid which inhibits hyperglycemia and also acts as a cardiovascular stimulant. Gymnema Sylvestre is commonly used to remove the taste of sugar, therefor reducing cravings for sweets.

Inositol is a carbocyclic polyol and a former member of the Vitamin B complex, listed as the Vitamin B8. Its most widely observed naturally occurring form is myo-inositol, which is found in many foods, such as high bran cereals, nuts beans, but also oranges and cantaloupe melons. Biological processes which are affected by inositol include the insulin signal transduction, nerve guidance in correlation with Epsin, cell membrane potential maintenance, serotonin activity modulation, cytoskeleton assembly, gene expression and breakdown of fats as well as reduction of blood cholesterol. Several psychiatric conditions can be treated with inositol, including obsessive compulsive disorder, clinical depression, panic disorder, bulimia and others. Due to all the positive influences, Vitamin B8 is a popular body building supplement; in particular the activity pertaining to the lipid metabolism is of essence.

L-Carnitine is yet another weight loss supplement that also is an antioxidant and has effects on male infertility, diabetes, and bone mass and fatty acid metabolism.