Caffeine may be the most popular legal addictive stimulant that is available to mankind. Besides coffee, tea, guarana and kola nut have excess amount of this xanthine alkaloid, which is actually acting as a psychoactive drug. In several plants, caffeine is an effective insect repellant, but this trimethylxanthine is deemed by the Food and Drug Administration as generally safe food substance. It is an antagonist of adenosine receptors. The effect of caffeine is individual and may more or less increase the ability to perform physical and mental labor. It reduces the effects of fatigue and may in long term help predominantly men reduce the risk of developing Parkinson’s disease. It has also been observed that caffeine has nootropic effects, furthermore, regular consumption of caffeine may significantly reduce the risk of heart diseases.

Citric Acid is found in several citrus fruits, including pineapples, limes, gooseberries, plums, peaches, lemons, grapefruit, and oranges. It assists in preventing urinary tract infections. It is also applied as a natural preservative in lieu of chemicals. It helps energy production within the cells. It is a good natural astringent and regulates pH in digestive tract. Citric acid boosts efficient digestive function and helps remove toxins from body. It provides prevention against diarrhea, dysentery, and other bowel diseases. Citric acid assists in breakdown of fatty foods and increasing appetite. It helps eliminate fatigue. Citric acid in a little modified form, potassium citrate, can halt human heartbeat for greater facility during surgery and also is used to leach damaging metals from soil in landfills.

Folic Acid is an essential water soluble vitamin. Though folic acid is needed for all age groups, folic acid supplements is necessary for aging people, pregnant women, smokers, women on oral contraceptives and heavy alcohol drinkers as their body have difficulty in absorbing folic acid through food. Folic acid has many vital functions to perform in our body. It helps in preventing heart disease, stroke, and may help prevent cervical, lung and colon cancer and helps in maturation of red blood cells. It’s recommended that pregnant women take folic acid supplementation through out pregnancy as it helps prevent premature delivery, low birth weight and fetal growth retardation. It may also help reduce the risk of renal disease in children and is necessary for fertility in both women and men. Some studies suggest that there is a relationship between folic acid and allergic diseases and depression. It also reduces risk of bone fractures, osteoporosis and helps prevent rheumatoid arthritis. It increases lipolysis and may help in preventing obesity and type 2 diabetes. In a study conducted it increased the short-term memory, mental agility and verbal fluency of people who consumed folic acid supplements (800mgs) daily. Folic acid supplements are also used to relieve hot flushes in postmenopausal women and helps correct anemia caused by vitamin B 12 deficiencies.

L-Glycine- Glycine is an organic compound and one of the 20 amino acids deemed as building blocks for proteins. This proteinogenic amino acid is not only the smallest but also the only amino acid of the group that is not chiral, which means there is no enantiomer of glycine. With the prominent exception of collagen, which thirty five percent are glycine, most proteins contain only small amounts of it. As a solid, glycine is sweet tasting, crystalline and has no color. Despite being non-essential, because it can be biosynthesized from the amino acid serine, glycine has several important physiological functions, besides being a precursor to proteins. It is a biosynthetic intermediate of purines and the D-Aminolevulinic acid and it is an inhibitory neurotransmitter found in the central nervous system.

L-Tyrosine is a non-essential amino acid, which is used by the cells in order to synthesize the proteins and appears to help stabilize ones mood during periods of high stress levels.

N-Acetyl L-Cysteine or "NAC" is derived from simple amino acid cysteine and is of great medicinal value. N-acetyl-cysteine has the ability to neutralize cell and DNA damaging free radicals and therefore plays an important role in slowing down the process of aging. As such, it protects us from a wide range of modern toxins including paraquat (a toxic herbicide), acrolein (present in cigarette smoke and auto exhaust), halothane (an anesthetic), adriamycin (both anticancer drugs) and hazardous side effects of cyclophosphamide. Apart from this toxin protection, it also facilitates in converting and synthesizing glutathione, an amino acid that is found in every cell. This amino acid comprises of glycine, L-glutamic acid, and L-cysteine, out of which glycine and L-glutamic acid are present in large quantities in our diets. Despite this, our bodies can produce glutathione only in limited quantities due to limited availability of cysteine. N-acetyl-cysteine supplements thus help the body increase production of glutathione.

Niacin is a vitamin that wards against pellagra, a disease characterized by a vitamin B3 deficiency. Niacin is made from pyridine and is often called vitamin B3 or nicotinamide, because they all three have similar formulas. Niacin and nicotinamide are comparable in make up, but only niacin works to lower cholesterol levels. The restoration of DNA is also known to be a positive side effect of taking niacin. A fairly large number of individuals, particularly those in third world countries or those suffering from alcoholism, have been shown to be lacking in niacin. Niacin is often taken as a supplement by those with high cholesterol levels, as it has been proven to lower “bad” cholesterol and raise “good” cholesterol.

Taurine ,an essential amino acid, contains cysteine and methoinine. It is normally added to energy drinks to improve the level of endurance during workouts. It acts like a diuretic and retains magnesium and potassium within the cells and gets rid of sodium. It helps eliminate swelling and accumulation of fluids and enhances the functioning of the kidney. Taurine also helps maintain a proper balance of calcium, lowers the blood pressure, prevent the development of gallstones and strengthens the muscles of the heart. Additionally, it even supports diabetes patients, as it inhibits resistance to insulin and hyperglycemia. Taurine deficiency can impair vision, develop epilepsy and could lead to problems like fat metabolism. It naturally detoxifies our body and is required in small doses of 1 and 4 grams everyday.

Vitamin B12, also known as cobalamin, which is naturally found in foods such as fish, milk and milk products, eggs, meat and poultry. Vitamin B12 is important for good health, necessary for the proper digestion and absorption of foods and for normal metabolism of carbohydrates, and fat. It helps maintain healthy nerve cells and red blood cells and is needed to make DNA. Vitamin B12 is bound to the protein in food. Hydrochloric acid in the stomach releases B12 from protein during digestion. Unlike other water-soluble nutrients, vitamin B12 is stored in the liver, kidney, and other body tissues. It can take several years before signs of the deficiency appear due to poor dietary intake. Vitamin B12 functions as a "methyl donor." A methyl donor is a compound that carries and donates methyl groups to other molecules, including cell membrane components and neurotransmitters. As a methyl donor vitamin B12 is involved in homocysteine metabolism and plays a critical role in proper energy metabolism, immune function, and nerve function. Therefore, vitamin B12 is clearly an added benefit for anyone wanting to lose weight, as without it, metabolism is not at its peak potential.

Vitamin B6, which active form pyridoxal phosphate or otherwise known as PLP and pyridoxal-5’-phosphate, is a prosthetic group of tightly bound cofactors responsible for many reactions within the amino acid metabolism and the manipulation of the enzymatic reaction behind the release of glucose from glycogen. Vitamin B6 generally comprises three organic compounds, pyridoxine, pyridoxal and pyridoxamine, all of them heterocyclic organic compounds that are converted in the human body to the active pyridoxal phosphate form. There are three reactions attributed to PLP, namely transamination, alpha elimination and beta elimination. Over one hundred and forty enzyme activities depend on pyridoxal phosphate, neurotransmitter and histamine synthesis, synthesis and function of hemoglobin, and gene expression. As a cofactor, PLP is active in amino acid metabolism, glucogenesis and lipid metabolism.

Vitamin C- The essential nutrient L-ascorbic acid, or rather Vitamin C, is necessary for a wide plethora of metabolic reactions in almost all living beings. In humans, Vitamin C is vital in the collagen synthesis. While most beings are able to make it internally, apes and humans cannot. Interestingly enough, while widely promoted as the best dietary source of Vitamin C, Oranges are dwarfed by the Kakadu plum, which has sixty times the amount. Prominent are rose hips, blackcurrant, red peppers, parsley, the kiwifruit, broccoli, redcurrant, several berries including strawberries and raspberries, as well as more exotic fruits and vegetables like Camu Camu, acerola, seabuckthorn, Indian gooseberry, jujube, guava and baobab. Tomatoes, while very popular Vitamin C source in the US, are very low on the Vitamin C scale.